However, experts haven’t stopped working on new and improved vaccinations for COVID-19 to keep us safe from the virus’s ever-evolving threats. When Pfizer and BioNTech revealed a new research on Omicron vaccines earlier this week, we were all excited.
Researchers selected 1,420 healthy adults, who will be some of the first people to get the experimental vaccination. The vaccine’s safety and tolerability will be evaluated during the clinical study, as well as the participants’ immunological responses.
What is the procedure for the clinical trial?
People of different vaccination statuses are being tested for the Omicron vaccine by the study team. Three primary groups of volunteers, all of whom are between the ages 18 and 55, have been selected for study:
Six hundred fifteen people from the current Pfizer-BioNTech COVID-19 vaccination are included in the first group. Researchers will administer either one or two doses of the novel Omicron vaccination to those who have already received both shots 90 to 180 days previous to joining in the study.
Six hundred people in the second group had received the latest Pfizer vaccination three times and had their most recent injection between 90 and 180 days prior to inclusion. A single dose of the current Pfizer vaccine or a single dose of the Omicron vaccine will be administered to this particular group.
There are 205 people in the third group who have never gotten a COVID-19 vaccination. The Omicron vaccination will be administered to these subjects three times.
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Why is an Omicron vaccination necessary?
It’s apparent that the current Pfizer and Moderna vaccines are effective. We are protected from serious infection by taking two doses, and a booster dose protects us much more. Early evidence, on the other hand, reveals that commercial vaccinations are less efficient than expected against Omicron.
Pfizer’s Kathrin U. Jansen, PhD, Senior Vice President, and Head of Vaccine Research and Development, said, “Although current research and real-world data show that boosters continue to provide a high level of protection against severe disease and hospitalisation with Omicron, we recognise the need to be prepared in the event this protection wanes over time and to potentially help address Omicron and new variants in the future.”
In order to retain a high level of protection against the virus, we must find new ways for people to maintain a high degree of protection and we believe developing and exploring variant-based vaccines, such as this one, are crucial in our efforts.
It will take some time to see the outcomes of this trial, but it’s a crucial step forward in the struggle against COVID-19.